Phosphorus sulfide (P2S5) → HCID 20494272、化合物
反応式
[Cl:1][C:2]1[C:3](=O)[NH:4][C:5](=[O:9])[NH:6][C:7]=1[CH3:8].P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:12]>O1CCOCC1>[Cl:1][C:2]1[C:3](=[S:12])[NH:4][C:5](=[O:9])[NH:6][C:7]=1[CH3:8]参加物
4
実験手順
5-Chloro-6-methyluracil (prepared as described in Johnson, B. T. J. Amer. Chem. Soc. 65 (1943) (1220) (0.018 mol) and phosphorus pentasulphide (0.019 mol) were heated together in refluxing dioxan (200 ml) for 45 min. The hot reaction mixture was then filtered and the cold filtrate concentrated and diluted with ether. The participate collected after a few hours in the cold, was recrystallised from water; yield 75% m.p. 297°-300° C. (decomp.); (Found: C, 32.69; H, 3.96. Calc. for C5H5ClN2OS.1/2H2O: C, 32.35; H, 3.25).
後処理
- filtrationThe hot reaction mixture was then filtered
- concentrationthe cold filtrate concentrated
- additiondiluted with ether
- customThe participate collected after a few hours in the cold,
- customwas recrystallised from water
出典と根拠
- ORDレコード
- ord-4144011a89304f38a047939c568a2deb
- 出典データセット
- uspto-grants-1983_07
- 特許番号
- US04395406
反応ノート
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