Acetic Anhydride → N-(3-(Pyridin-2-yl)phenyl)acetamide

HRID 1075453ノート

反応式

HRID 1075453 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[CH:8]=[C:9]([CH:11]=[CH:12][CH:13]=1)[NH2:10].[OH-].[Na+].[C:16](OC(=O)C)(=[O:18])[CH3:17]>>[C:16]([NH:10][C:9]1[CH:11]=[CH:12][CH:13]=[C:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)[CH:8]=1)(=[O:18])[CH3:17]

参加物

4

反応物 3

HCID 7918Acetic AnhydrideHCID 14798Sodium HydroxideHCID 4595173-(2-Pyridyl)aniline

生成物 1

HCID 53737528N-(3-(Pyridin-2-yl)phenyl)acetamide

実験手順

A mixture of 2f (5.6g, 32.9mmol) and acetic anhydride (20ml) is stirred at ambient temperature for 1 hour. The mixture is poured into ice-water and rendered alkaline with 10M sodium hydroxide. The product is filtered off, washed with water and dried. Yield:

後処理

  1. filtrationThe product is filtered off
  2. washwashed with water
  3. customdried

出典と根拠

ORDレコード
ord-2619935c8ef140c9a0e3f1699844ece5
出典データセット
uspto-grants-1999_05
特許番号
US05902813

反応ノート

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