HCID 13124491、化合物 → HCID 15428308、化合物
反応式
C(OC([NH:11][C@H:12]1[C@H:15]([O:16][C:17](=[O:19])[CH3:18])[NH:14][C:13]1=[O:20])=O)C1C=CC=CC=1.[H][H]>[Pd].C(OCC)(=O)C>[NH2:11][C@H:12]1[C@H:15]([O:16][C:17](=[O:19])[CH3:18])[NH:14][C:13]1=[O:20]参加物
5
実験手順
(3S,4S)-3-benzyloxycarbonylamino-4-acetoxy-azetidin-2-one (6.00 g, 21.6 mmole) was hydrogenated with 6 g of 10% palladium on activated carbon in ethyl acetate (150 ml) at 50 psi hydrogen pressure at room temperature for 1.5 hrs. after removal of catalyst by filtration, the deproteced (3S,4S)-3-amino-4-acetoxy-azetidin-2-one in ethyl acetate was obtained.
後処理
- customafter removal of catalyst
- filtrationby filtration
出典と根拠
- ORDレコード
- ord-d88ded29c74f44419ac75032d48fc1a7
- 出典データセット
- uspto-grants-1999_05
- 特許番号
- US05905076
反応ノート
読み込み中…