Ethanol → HCID 86754078、化合物

HRID 1075699ノート

反応式

HRID 1075699 の反応式
C([NH:4][CH2:5][CH2:6][O:7][CH2:8][C:9]([O-:11])=[O:10])(=O)C.[Na+:12].[OH-].[Na+].CCO>O>[NH2:4][CH2:5][CH2:6][O:7][CH2:8][C:9]([O-:11])=[O:10].[Na+:12]

参加物

5

反応物 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 86754077HCID 86754077、化合物

生成物 1

HCID 86754078HCID 86754078、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
100 °C

実験手順

52 g of sodium 5-acetylamino-3-oxapentanoate were dissolved in 200 ml of water. 11.4 g of NaOH were added at 20° C., and the reaction mixture was then heated at 100° C. for 8 h until precursor was no longer detectable. Then 200 ml of EtOH were added and the pH was adjusted to about 6, resulting in pure crystals of sodium 5-amino-3-oxapentanoate. The crude product resulting after removal of the solvent by distillation as a mixture with sodium acetate weighing 63.3 g (corresponding to 100% of theory) could be employed without prior precipitation for the subsequent reaction.

出典と根拠

ORDレコード
ord-73112dd8f6c24967aaee3dc92f68f0da
出典データセット
uspto-grants-1999_05
特許番号
US05907055

反応ノート

読み込み中…