Dimethylamine → HCID 21540598、化合物
反応式
Cl[C:2]1[C:3]([C:17]([F:20])([F:19])[F:18])=[CH:4][C:5]2[N:9]=[C:8]([CH3:10])[N:7]([CH2:11][CH3:12])[C:6]=2[C:13]=1[N+:14]([O-:16])=[O:15].[CH3:21][NH:22][CH3:23]>C(COC)OC>[CH3:21][N:22]([CH3:23])[C:2]1[C:3]([C:17]([F:20])([F:19])[F:18])=[CH:4][C:5]2[N:9]=[C:8]([CH3:10])[N:7]([CH2:11][CH3:12])[C:6]=2[C:13]=1[N+:14]([O-:16])=[O:15]参加物
4
反応条件
- 温度
- 125 °C
実験手順
A glass reaction tube was charged with 5.0g. (0.016 mole) of 6-chloro-1-ethyl-2-methyl-7-nitro-5-trifluoromethylbenzimidazole, 20 ml. of dimethoxyethane and 15 ml. of dimethylamine and then sealed. The sealed tube was maintained at 125°C. for 16 days and then opened. The contents were evaporated to dryness and the residue extracted with hot hexane, from which crystallized 3.1g. of the desired product m.p. 111°-115°C. after recrystallization from hexane.