Formic Acid → 3,9-dimethyl-2-hydroxymethyl-9H-dibenzo [b,f]-imidazo[1,2-d][1,4]diazepine

反応式

[CH3:1][C:2]1[N:6]2[C:7]3[CH:19]=[CH:18][CH:17]=[CH:16][C:8]=3[NH:9][C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=3[C:5]2=[N:4][CH:3]=1.[CH2:20]=O.[CH:22]([OH:24])=O>>[CH3:1][C:2]1[N:6]2[C:7]3[CH:19]=[CH:18][CH:17]=[CH:16][C:8]=3[N:9]([CH3:20])[C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=3[C:5]2=[N:4][C:3]=1[CH2:22][OH:24]

参加物

反応物 3

HCID 284Formic Acid

HCID 712Formaldehyde

HCID 30466853-methyl-9H-dibenzo[b,f]imidazo[1,2-d][1,4]diazepine

生成物 1

HCID 536579033,9-dimethyl-2-hydroxymethyl-9H-dibenzo [b,f]-imidazo[1,2-d][1,4]diazepine

実験手順

3-methyl-9H-dibenzo[b,f]imidazo[1,2-d][1,4]diazepine is dissolved in 88% formic acid, treated with 37% aqueous formalin solution and heated for 24 hours, to give 3,9-dimethyl-2-hydroxymethyl-9H-dibenzo [b,f]-imidazo[1,2-d][1,4]diazepine.