Z-Asn-Leu-OMe → H-Asn-Leu-OMe
反応式
[NH:1](C(OCC1C=CC=CC=1)=O)[C@H:2]([C:7]([NH:9][C@H:10]([C:15]([O:17][CH3:18])=[O:16])[CH2:11][CH:12]([CH3:14])[CH3:13])=[O:8])[CH2:3][C:4](=[O:6])[NH2:5]>C(O)(C)(C)C.O.[Pd]>[NH2:1][C@H:2]([C:7]([NH:9][C@H:10]([C:15]([O:17][CH3:18])=[O:16])[CH2:11][CH:12]([CH3:14])[CH3:13])=[O:8])[CH2:3][C:4](=[O:6])[NH2:5]参加物
4
実験手順
15.0 g of Z-Asn-Leu-OMe are dissolved in 400 ml of t-butanol-water (9:1) and are hydrogenated in the presence of 2 g of palladium-charcoal (10 %Pd). After completion of the hydrogenation the catalyst is filtered off and the solution evaporated at 40°C. The residue is directly further used.
後処理
- filtrationAfter completion of the hydrogenation the catalyst is filtered off
- customthe solution evaporated at 40°C
出典と根拠
- ORDレコード
- ord-1c356ee9e6404bc89f2822edbada4893
- 出典データセット
- uspto-grants-1976_05
- 特許番号
- US03956260
反応ノート
読み込み中…