Pyridine → 2-[(4-Chlorophenyl)sulfanyl]ethyl cyclopropanecarboxylate

HRID 1076760ノート

反応式

HRID 1076760 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH2:10][OH:11])=[CH:4][CH:3]=1.[CH:12]1([C:15](Cl)=[O:16])[CH2:14][CH2:13]1.N1C=CC=CC=1>CCOCC>[CH:12]1([C:15]([O:11][CH2:10][CH2:9][S:8][C:5]2[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=2)=[O:16])[CH2:14][CH2:13]1

参加物

5

反応物 3

HCID 1049PyridineHCID 77637Cyclopropanecarbonyl chlorideHCID 834872-(p-Chlorophenylthio)ethanol

生成物 1

HCID 214896452-[(4-Chlorophenyl)sulfanyl]ethyl cyclopropanecarboxylate

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

To a mixture of 1.88 g. 2-(4-chlorophenylthio)ethanol and 1.35 g. cyclopropylcarboxylic acid chloride in 50 ml. ether is added 2 equivalents pyridine. The reaction mixture is stirred overnight at room temperature and worked up as in Example 5 to yield 2-(4-chlorophenylthio)ethyl cyclopropanecarboxylate.

後処理

  1. additionTo a mixture of 1.88 g

出典と根拠

ORDレコード
ord-de40b994676a4b5f8e160d836ae9d74f
出典データセット
uspto-grants-1976_05
特許番号
US03957849

反応ノート

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