Oxalyl chloride → HCID 18999946、化合物
反応式
[CH3:1][CH:2]([CH3:10])[CH2:3][CH2:4][C:5](=[O:9])[C:6](O)=[O:7].C(Cl)(=O)C([Cl:14])=O>>[CH3:1][CH:2]([CH3:10])[CH2:3][CH2:4][C:5](=[O:9])[C:6]([Cl:14])=[O:7]参加物
3
実験手順
The 5-methyl-2-oxohexanoic acid is reacted with at least a 10% excess over the stoichiometric amount of oxalyl chloride to form 5-methyl-2-oxohexanoyl chloride [reaction (4)]. ##EQU6## Oxalyl chloride is a suitable solvent for reaction (4), and theoretically can be present in an unlimited excess over stoichiometry. Solvents such as diethyl ether, petroleum ether, benzene, CH2Cl2, and hexane are also suitable solvents for the reaction. The use of solvents is preferred but is not necessary. Reaction (4) must be run under anhydrous conditions in an inert atmosphere and requires from 40 to 60 hours at a temperature of from 25° to 60° C. for completion.
出典と根拠
- ORDレコード
- ord-2077c4052ccb4e8f946c101dfdcd0840
- 出典データセット
- uspto-grants-1976_05
- 特許番号
- US03959312
反応ノート
読み込み中…