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HRID 1077489作成日:2026年10月27日

3-(1,3-Benzodioxol-5-yl)prop-2-enoic acid → 1H-Purine-2,6-dione, 8-((1E)-2-(1,3-benzodioxol-5-yl)ethenyl)-3,7-dihydro-1,3-dimethyl-

https://huagongshe.com/reaction/1077489

反応式

関与物質

役割名称HCID仕込み量
反応物3-(1,3-Benzodioxol-5-yl)prop-2-enoic acidHCID 16917—
反応物5,6-Diamino-1,3-dimethyluracilHCID 79501—
生成物1H-Purine-2,6-dione, 8-((1E)-2-(1,3-benzodioxol-5-yl)ethenyl)-3,7-dihydro-1,3-dimethyl-HCID 606200213%

反応手順

Substantially the same procedure as in Reference Example 70 was repeated using 5.0 g (29.4 retool) of 5,6-diamino-1,3-dimethyluracil and 6.78 g (35.3 mmol) of 3,4-methylenedioxycinnamic acid. Then, the resultant crude crystals were recrystallized from dimethylformamide/water to give 1.20 g (yield 13%) of Compound 95 as a pale yellow powder.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05543415
出典データセットuspto-grants-1996_08
ORD IDord-7be1d4d496cf4c3bb0e2158a198752ec
出典メモuspto-grants-1996_08