3,4-Dimethylbenzoic acid → 3,4-Dimethylbenzoyl chloride

HRID 1078346

反応式

HRID 1078346 の反応式
S(Cl)([Cl:3])=O.[CH3:5][C:6]1[CH:7]=[C:8]([CH:12]=[CH:13][C:14]=1[CH3:15])[C:9](O)=[O:10]>>[CH3:5][C:6]1[CH:7]=[C:8]([CH:12]=[CH:13][C:14]=1[CH3:15])[C:9]([Cl:3])=[O:10]

参加物

3

反応物 2

HCID 120733,4-Dimethylbenzoic acidHCID 24386Thionyl Chloride

生成物 1

HCID 27585353,4-Dimethylbenzoyl chloride収率 94.4%

実験手順

78 g of thionyl chloride were added to 50 g of 3,4-dimethylbenzoic acid and the reaction mixture was heated at reflux for 3 hours. The reaction mixture was subsequently concentrated, and the residue was taken up twice in toluene and concentrated again. 53 g of 3,4-dimethylbenzoyl chloride were obtained.

後処理

  1. temperaturethe reaction mixture was heated
  2. temperatureat reflux for 3 hours
  3. concentrationThe reaction mixture was subsequently concentrated
  4. concentrationconcentrated again

出典と根拠

ORDレコード
ord-10b2432107f14a44882b92f914b359dc
出典データセット
uspto-grants-1996_08
特許番号
US05547967

関連ノート

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