Pyridine → HCID 15168935、化合物
反応式
Cl[C:2]1[C:7]([C:8]([NH:10][C:11]2[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][C:12]=2[OH:18])=[O:9])=[CH:6][C:5]([N+:19]([O-:21])=[O:20])=[CH:4][N:3]=1.N1C=CC=CC=1>O>[N+:19]([C:5]1[CH:4]=[N:3][C:2]2[O:18][C:12]3[CH:13]=[C:14]([CH3:17])[CH:15]=[CH:16][C:11]=3[NH:10][C:8](=[O:9])[C:7]=2[CH:6]=1)([O-:21])=[O:20]参加物
4
反応条件
- 温度
- 90 °C
実験手順
A mixture of 2-chloro-5-nitro-N-(3-hydroxytol-4-yl)-3-pyridinecarboxamide (6.3 g, 0.02 mol) and pyridine (100 ml) was heated under argon at 90° C. for 2.5 hours. The cooled solution was diluted with water and the yellow-orange precipitate collected and washed with water. The solid was then stirred in hot water (100 ml) for 45 min., filtered and washed with ethanol and ether to give 4.3 g of a tan-brown solid. Recrystallization from dimethylformamide/water afforded 3.76 g (69% of theory) of product.