Thiazole → 3-(2-Hydroxyethyl)-1,3-thiazol-3-ium bromide

HRID 1080180ノート

反応式

HRID 1080180 の反応式
[S:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.[Br:6][CH2:7][CH2:8][OH:9]>>[Br-:6].[OH:9][CH2:8][CH2:7][N+:3]1[CH:4]=[CH:5][S:1][CH:2]=1

参加物

3

反応物 2

HCID 9256ThiazoleHCID 108982-Bromoethanol

生成物 1

HCID 138881473-(2-Hydroxyethyl)-1,3-thiazol-3-ium bromide

実験手順

Thiazole (4.3 g) and 2-bromoethanol (12.5 g) were mixed and heated under reflux for 5 hours. The reaction was left standing at room temperature to give white needles. The crystals were washed with acetone, collected by filtration and dried under reduced pressure.

後処理

  1. temperatureheated
  2. temperatureunder reflux for 5 hours
  3. waitThe reaction was left
  4. customstanding at room temperature
  5. customto give white needles
  6. washThe crystals were washed with acetone
  7. filtrationcollected by filtration
  8. customdried under reduced pressure

出典と根拠

ORDレコード
ord-6d8ff83a71c74d93878a9c194cdb7a9b
出典データセット
uspto-grants-1996_12
特許番号
US05580904

反応ノート

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