Bicine → Glycine, N,N-bis(2-hydroxyethyl)-, sodium salt (1:1)

N,N-Bis-(2-hydroxyethyl)aminoacetic acid (364.933 grams, 2.2144 moles) (this material is 99% pure; it contains 1% or 3.613 grams of H2O) is added with stirring to a cooled solution of pure sodium hydroxide (88.57 grams, 2.2144 moles) in pyrogen-free distilled water (400 ml.). The mixture is stirred until solution is effected. After reaching room temperature, the solution is stirred while enough pyrogen-free distilled water is added to make the total volume 1,000 ml. The solution is sterilized by filtration. This solution is 41% or 2.2144 molar in sodium N,N-bis-(2-hydroxyethyl)aminoacetate.

1. additionis added
2. distillationin pyrogen-free distilled water (400 ml.)
3. customAfter reaching room temperature
4. stirringthe solution is stirred while enough
5. distillationpyrogen-free distilled water
6. additionis added
7. filtrationThe solution is sterilized by filtration

ORDレコード

ord-870ee97d615d4865a2423c22c6fa68a2

出典データセット

uspto-grants-1996_12

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US05585391