反応式
[F:1][C:2]1[CH:3]=[C:4]([O:9][CH3:10])[CH:5]=[CH:6][C:7]=1[F:8].[Li+].CCC[CH2-].C[O:17]B(OC)OC.Cl.OO>CCCCCC>[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[C:4]([O:9][CH3:10])[C:3]=1[OH:17]参加物
7
実験手順
Using the procedure of Example 39, 125 g of 3,4-difluoroanisole (commercial) and 500 ml of a 1.6 M solution of N-butyllithium in hexane were reacted at -72° C., and then 92.4 ml of trimethylborate, 500 ml of hydrochloric acid and 120 g of intermediate compound were reacted and the product was reacted with 440 ml of 30% hydrogen peroxide to obtain 82.4 g of the expected product melting at 46.6° C.
後処理
- customwere reacted at -72° C.
出典と根拠
- ORDレコード
- ord-07338b9d1ccd436aa5fb1ae9d73c2a48
- 出典データセット
- uspto-grants-1996_12
- 特許番号
- US05587372
関連ノート
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