Chlorosulfonic acid → HCID 20062876、化合物

HRID 1084923ノート

反応式

HRID 1084923 の反応式
[O:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[C:11]([OH:13])=[O:12])[CH2:4][CH2:3][CH2:2]1.[Cl:14][S:15](O)(=[O:17])=[O:16]>>[Cl:14][S:15]([C:7]1[CH:6]=[C:5]2[C:10](=[C:9]([C:11]([OH:13])=[O:12])[CH:8]=1)[O:1][CH2:2][CH2:3][CH2:4]2)(=[O:17])=[O:16]

参加物

3

反応物 2

HCID 24638Chlorosulfonic acidHCID 127011383,4-Dihydro-2H-1-benzopyran-8-carboxylic acid

生成物 1

HCID 20062876HCID 20062876、化合物

反応条件

温度
10 °C

実験手順

930 ml of chlorosulphonic acid were introduced into a 1-liter round-bottomed flask and 165 g of chroman-8-carboxylic acid were then added in small amounts, while maintaining the temperature between 0° C. and 10° C. by cooling. The solution was stirred for 1 hour at 10° C., and then allowed to stand overnight at ambient temperature. It was then poured in small amounts onto ice, while stirring and maintaining the temperature at 0° C. by cooling externally and by introducing ice into the flask.

後処理

  1. temperaturewhile maintaining the temperature between 0° C. and 10° C.
  2. temperatureby cooling
  3. waitto stand overnight at ambient temperature
  4. additionIt was then poured in small amounts onto ice
  5. stirringwhile stirring
  6. temperaturemaintaining the temperature at 0° C.
  7. temperatureby cooling externally
  8. additionby introducing ice into the flask

出典と根拠

ORDレコード
ord-5fa4fc8f909f4345a9e17994857f68f8
出典データセット
uspto-grants-1991_04
特許番号
US05006570

反応ノート

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