Methyl cyclohexanecarboxylate → Cyclohexanecarbohydrazide

HRID 1085112

反応式

HRID 1085112 の反応式
[CH:1]1([C:7]([O:9]C)=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:11][NH2:12].O>C(O)(C)C>[CH:1]1([C:7]([NH:11][NH2:12])=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

4

反応物 2

HCID 20748Methyl cyclohexanecarboxylateHCID 24654Hydrazine hydrate (1:1)

生成物 1

HCID 240039Cyclohexanecarbohydrazide

試薬・触媒・溶媒 1

HCID 3776Isopropanol溶媒

実験手順

28 Grams of methyl cyclohexylcarboxylate and 15 g of 85%-NH2NH2.H2O were dissolved in 50 ml of isopropyl alcohol, and the solution was refluxed by heating for 10 hours. The reaction mixture was concentrated, and the crystals precipitated by adding water were collected by filtration, then the crystals were washed with water, then recrystallized from water to yield 20 g of cyclohexanecarbohydrazide in the form of colorless needle-like crystals.

後処理

  1. temperaturethe solution was refluxed
  2. temperatureby heating for 10 hours
  3. concentrationThe reaction mixture was concentrated
  4. customthe crystals precipitated
  5. additionby adding water
  6. filtrationwere collected by filtration
  7. washthe crystals were washed with water
  8. customrecrystallized from water

出典と根拠

ORDレコード
ord-2cb69bdc3bbd47d58486164b0447b5d6
出典データセット
uspto-grants-1991_04
特許番号
US05008274

関連ノート

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