4-Hydroxy-4-trifluoromethyl-2,5-cyclohexadien-1-one → 4-Hydroxy-4-(trifluoromethyl)cyclohexan-1-one

HRID 1085348ノート

反応式

HRID 1085348 の反応式
[OH:1][C:2]1([C:9]([F:12])([F:11])[F:10])[CH:7]=[CH:6][C:5](=[O:8])[CH:4]=[CH:3]1.[H][H]>C(O)C.[Pd]>[OH:1][C:2]1([C:9]([F:10])([F:11])[F:12])[CH2:3][CH2:4][C:5](=[O:8])[CH2:6][CH2:7]1

参加物

5

反応物 2

HCID 138691094-Hydroxy-4-trifluoromethyl-2,5-cyclohexadien-1-oneHCID 178418361HCID 178418361、化合物

生成物 1

HCID 200351424-Hydroxy-4-(trifluoromethyl)cyclohexan-1-one

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A solution of 100 mg of 4-hydroxy-4-trifluoromethyl -2,5-cyclohexadien-1-one in 1 mL of absolute ethanol was treated with a few mg of 5% palladium on carbon, hydrogenated in a Parr shaker for one hour under 50 psig of hydrogen, and filtered. Gas chromatographic/mass spectral analysis indicated that the major component of the filtrate was 4-hydroxy-4-trifluoromethylcyclo hexanone: mass spectrum (70 eV) m/z (relative intensity) 182 (11, M+), 55 (100), 42 (40).

後処理

  1. filtrationfiltered

出典と根拠

ORDレコード
ord-98e5fa0059b84be1bafcd729cf8c8e86
出典データセット
uspto-grants-1991_04
特許番号
US05008425

反応ノート

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