Hydrazine hydrate (1:1) → HCID 20060099、化合物

HRID 1085465ノート

反応式

HRID 1085465 の反応式
Cl[C:2]1[N:7]=[C:6]([CH3:8])[CH:5]=[C:4]([CH:9]2[CH2:11][CH2:10]2)[N:3]=1.O.[NH2:13][NH2:14]>C(O)C>[NH:13]([C:2]1[N:7]=[C:6]([CH3:8])[CH:5]=[C:4]([CH:9]2[CH2:11][CH2:10]2)[N:3]=1)[NH2:14]

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 19804698HCID 19804698、化合物

生成物 1

HCID 20060099HCID 20060099、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

3.0 g of 2-chloro-4-methyl-6-cyclopropylpyrimidine are dissolved in 30 ml of ethanol; 3.8 ml of hydrazine hydrate are added and the mixture is stirred for 20 hours at room temperature. The solvent is then evaporated off in vacuo and the residue is recrystallised with ethyl acetate. M.p. 98°-99° C.

後処理

  1. customThe solvent is then evaporated off in vacuo
  2. customthe residue is recrystallised with ethyl acetate

出典と根拠

ORDレコード
ord-80d05987f4c04b3f87a30da479f6ac04
出典データセット
uspto-grants-1991_04
特許番号
US05010082

反応ノート

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