HCID 15725169、化合物 → HCID 15725170、化合物
反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH:9]2[CH2:14][CH2:13][CH:12]([O:15]CC3C=CC=CC=3)[CH2:11][CH2:10]2)=[CH:4][CH:3]=1.[H][H]>[Pd].CO>[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:8][CH:9]2[CH2:10][CH2:11][CH:12]([OH:15])[CH2:13][CH2:14]2)=[CH:6][CH:7]=1参加物
5
実験手順
A mixture of 17.1 parts of 1-fluoro-4-[[4-(phenylmethoxy)cyclohexyl]oxy]benzene and 160 parts of methanol was hydrogenated at normal pressure and at room temperature with 2 parts of palladium-on-charcoal catalyst 10%. After the calculated amount of hydrogen was taken up, the catalyst was filtered off over Hyflo and the filtrate was evaporated, yielding 8.9 parts (74.3%) of 4-(4-fluorophenoxy)cyclohexanol as a residue (139).
後処理
- filtrationthe catalyst was filtered off over Hyflo
- customthe filtrate was evaporated
出典と根拠
- ORDレコード
- ord-b4454e1368914596b54a53b23704e138
- 出典データセット
- uspto-grants-1991_04
- 特許番号
- US05010198
反応ノート
読み込み中…