4-Acetylpyridine → Phenyl [1-(4-pyridinyl)ethylidene]carbazate monohydrochloride
反応式
[C:1]([C:4]1[CH:9]=[CH:8][N:7]=[CH:6][CH:5]=1)(=O)[CH3:2].[ClH:10].[C:11]([O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)(=[O:14])[NH:12][NH2:13]>C(O)C>[ClH:10].[N:7]1[CH:8]=[CH:9][C:4]([C:1](=[N:13][NH:12][C:11]([O:15][C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)=[O:14])[CH3:2])=[CH:5][CH:6]=1参加物
4
実験手順
A mixture of 12.11 gm (0.1 mole) of 4-acetylpyridine, 18.85 gm (0.1 mole) of phenyl carbazate hydrochloride and 250 ml of absolute ethanol is refluxed 6 hr and cooled. The reaction mixture is evaporated to dryness in vacuo to give a rose-colored solid. The crude product is crystallized from absolute ethanol to yield 28.13 gm (97%) of the title compound having a melting point of 159.1° C.