4-Acetylpyridine → Cyclohexanecarboxylic acid [1-(4-pyridinyl)ethylidene]hydrazide

HRID 1085964

反応式

HRID 1085964 の反応式
[CH:1]1([C:7]([NH:9][NH2:10])=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:11]([C:14]1[CH:19]=[CH:18][N:17]=[CH:16][CH:15]=1)(=O)[CH3:12]>C(O)C>[N:17]1[CH:18]=[CH:19][C:14]([C:11](=[N:10][NH:9][C:7]([CH:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)=[O:8])[CH3:12])=[CH:15][CH:16]=1

参加物

4

反応物 2

HCID 142824-AcetylpyridineHCID 240039Cyclohexanecarbohydrazide

生成物 1

HCID 3337581Cyclohexanecarboxylic acid [1-(4-pyridinyl)ethylidene]hydrazide収率 73.1%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A solution of 4.26 gm (0.03 mole) of cyclohexanecarboxylic acid hydrazide, 3.63 gm (0.03 mole) of 4-acetylpyridine and 100 ml of ethanol is refluxed 7 hr. The solvent is evaporated in vacuo to give a white solid. The product is crystallized from ethyl acetate to yield 5.38 gm (73%) of the title compound having a melting point of 195.3° C.

後処理

  1. customThe solvent is evaporated in vacuo
  2. customto give a white solid
  3. customThe product is crystallized from ethyl acetate

出典と根拠

ORDレコード
ord-074e7e8d13724821a24658b9785b6b98
出典データセット
uspto-grants-1991_04
特許番号
US05011932

関連ノート

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