Ethanolamine → 2-Pentyl-2-oxazoline

HRID 1086420

反応式

HRID 1086420 の反応式
[C:1](#[N:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].C(C#N)CCCCCCCCCC.[CH2:21]([CH2:23]N)[OH:22]>O.O.C([O-])(=O)C.[Zn+2].C([O-])(=O)C>[CH2:2]([C:1]1[O:22][CH2:21][CH2:23][N:7]=1)[CH2:3][CH2:4][CH2:5][CH3:6]

参加物

5

反応物 3

HCID 700EthanolamineHCID 12352HexanenitrileHCID 17092Dodecanenitrile

生成物 1

HCID 146517902-Pentyl-2-oxazoline収率 60%

試薬・触媒・溶媒 1

HCID 2724192Zinc acetate (USP)触媒

実験手順

9.72 g (100 mmoles) of hexanenitrile was substituted for undecyl cyanide in Example 1 and the reaction was repeated with 6.11 g (100 mmoles) of ethanolamine and 549 mg (2.5 mmoles) of zinc acetate dihydrate under identical conditions. At the end of the reaction the product was worked up as before and distilled at 73° C./10 mm to give 8.2 g (60%) of 2-pentyl-2-oxazoline.

後処理

  1. customAt the end of the reaction the product
  2. distillationdistilled at 73° C./10 mm

出典と根拠

ORDレコード
ord-5dac6adbfadc472fa1136602ebb1d453
出典データセット
uspto-grants-1991_07
特許番号
US05030629

関連ノート

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