Amino-6-ethoxybenzothiazole, 2- → N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-methoxyacetamide
反応式
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([O:11][CH2:12][CH3:13])[CH:8]=[CH:7][C:5]=2[N:6]=1.[CH3:14][O:15][CH2:16][C:17](Cl)=[O:18]>N1C=CC=CC=1>[CH2:12]([O:11][C:9]1[CH:8]=[CH:7][C:5]2[N:6]=[C:2]([NH:1][C:17](=[O:18])[CH2:16][O:15][CH3:14])[S:3][C:4]=2[CH:10]=1)[CH3:13]参加物
4
実験手順
2-Amino-6-ethoxybenzothiazole (5.8 g) is dissolved in pyridine (100 ml) and thereto is added dropwise methoxyacetyl chloride (3.0 ml) at room temperature. After the mixture is stirred at room temperature for 2 hours, the solvent is distilled off. The resulting solids are washed with water, then with diethyl ether, dried and recrystallized from ethanol to give the title compound (5.1 g) having the following physical properties.
後処理
- distillationthe solvent is distilled off
- washThe resulting solids are washed with water
- dry with materialwith diethyl ether, dried
- customrecrystallized from ethanol
出典と根拠
- ORDレコード
- ord-f05414f5b307422c99104486583775b9
- 出典データセット
- uspto-grants-1991_07
- 特許番号
- US05036086
反応ノート
読み込み中…