Hydrochloric Acid → HCID 10997166、化合物

HRID 1088201ノート

反応式

HRID 1088201 の反応式
[CH3:1][C:2]([CH3:9])([CH3:8])[C:3]#[C:4][C:5](O)=[O:6].S(Cl)([Cl:12])=O.Cl>C(Cl)Cl>[CH3:1][C:2]([CH3:9])([CH3:8])[C:3]#[C:4][C:5]([Cl:12])=[O:6]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 24386Thionyl ChlorideHCID 128402174,4-Dimethylpent-2-ynoic acid

生成物 1

HCID 10997166HCID 10997166、化合物

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

466 g of 4,4-dimethyl-2-pentynoic acid was blended with 3.5 liters of methylene chloride and stirred. 483 g of thionyl chloride was added thereto and reacted for 1 hour and then heated under reflux, whereby a hydrogen chloride gas was vigorously generated. After the reaction system was heated under reflux for 2 hours, the solvent was distilled away under reduced pressure. The product was a colorless liquid having a boiling point of about 70° C. at 20 mm Hg. Yield: 290 g, 54.3%.

後処理

  1. customreacted for 1 hour
  2. temperatureheated
  3. temperatureunder reflux
  4. temperatureAfter the reaction system was heated
  5. temperatureunder reflux for 2 hours
  6. distillationthe solvent was distilled away under reduced pressure

出典と根拠

ORDレコード
ord-c39ea43975d54f6b8157e925eaee9cea
出典データセット
uspto-grants-1990_10
特許番号
US04962017

反応ノート

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