Guanidine Hydrochloride → HCID 14718745、化合物
反応式
C[O-].[Na+].Cl.[NH2:5][C:6]([NH2:8])=[NH:7].CN(C)[CH:11]=[C:12]([CH:22]=O)[CH:13]([CH:19]([CH3:21])[CH3:20])[C:14]([O:16][CH2:17][CH3:18])=[O:15]>C(O)C>[NH2:7][C:6]1[N:8]=[CH:11][C:12]([CH:13]([CH:19]([CH3:20])[CH3:21])[C:14]([O:16][CH2:17][CH3:18])=[O:15])=[CH:22][N:5]=1参加物
5
実験手順
A solution of sodium methoxide (0.9 g) in ethanol (5 cm3) was added dropwise to a stirred suspension of guanidine hydrochloride (1.58 g) and ethyl (RS)-4-dimethylamino-3-formyl-2-(1-methylethyl)-3-butenoate in ethanol (10 cm3). The reaction mixture was heated at the reflux temperature for 2 hours, then stood at the ambient temperature for 70 hours. The solvent was evaporated under reduced pressure and water added to the residue.
後処理
- temperatureThe reaction mixture was heated at the reflux temperature for 2 hours
- customThe solvent was evaporated under reduced pressure and water
- additionadded to the residue
出典と根拠
- ORDレコード
- ord-4a21f77aebe246cf90072f3b2426c1d1
- 出典データセット
- uspto-grants-1990_10
- 特許番号
- US04962109
反応ノート
読み込み中…