Methyl p-toluenesulfonate → HCID 86744275、化合物

HRID 1088577

反応式

HRID 1088577 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][CH2:9][OH:10])[CH:2]=1.[C:11]1([CH3:22])[CH:16]=[CH:15][C:14]([S:17]([O:20]C)(=[O:19])=[O:18])=[CH:13][CH:12]=1>CC(C)=O>[C:11]1([CH3:22])[CH:12]=[CH:13][C:14]([S:17]([O-:20])(=[O:18])=[O:19])=[CH:15][CH:16]=1.[OH:10][CH2:9][CH:8]=[CH:7][C:3]1[CH:2]=[N+:1]([CH3:11])[CH:6]=[CH:5][CH:4]=1

参加物

4

反応物 2

HCID 6645Methyl p-toluenesulfonateHCID 35635042-Propen-1-ol, 3-(3-pyridinyl)-

生成物 1

HCID 86744275HCID 86744275、化合物

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

Ethyl 3-(3-pyridyl)acrylate was reduced using lithium aluminum hydride to give 3-(3-pyridyl)-2-propen-1-ol. In 30 ml of acetone 710 mg of 3-(3-pyridyl)-2-propen-1-ol and 980 mg of methyl p-toluenesulfonate were heated under reflux for 22 hours. The reaction mixture was subjected by decantation to remove the solvent and then washed with acetone and ether. The residue was dried under reduced pressure to give 1.3 g of the desired compound as an orange-colored oil.

後処理

  1. temperatureunder reflux for 22 hours
  2. customto remove the solvent
  3. washwashed with acetone and ether
  4. customThe residue was dried under reduced pressure

出典と根拠

ORDレコード
ord-ab0bd96f038e4c9a91427c8f4d4a31c1
出典データセット
uspto-grants-1990_10
特許番号
US04962096

関連ノート

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