化工社化工社 化学情報印刷レポート · 研究参考用
8-(Bromomethyl)quinoline → 8-Quinolinemethanol,acetate(ester)
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 8-(Bromomethyl)quinoline | HCID 346914 | — |
| 反応物 | Sodium Acetate | HCID 517045 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 8-Quinolinemethanol,acetate(ester) | HCID 15053140 | 85.5% |
反応手順
8-Bromomethylquinoline (1.11 g) and sodium acetate (0.82 g) were suspended and dissolved in dimethyl formamide, and heated for 2 hours at 80° to 90° C. After completion of the reaction, dimethyl formamide was distilled off, and the residue was extracted with a mixed solvent of ethyl acetate-toluene (3:1). The solvent was distilled off to give 8-acetoxymethylquinoline (0.86 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04963566 |
| 出典データセット | uspto-grants-1990_10 |
| ORD ID | ord-d22eefa4c1ef4d9eb230b06c54d466d0 |
| 出典メモ | uspto-grants-1990_10 |