反应详情

8-Bromomethylquinoline (1.11 g) and sodium acetate (0.82 g) were suspended and dissolved in dimethyl formamide, and heated for 2 hours at 80° to 90° C. After completion of the reaction, dimethyl formamide was distilled off, and the residue was extracted with a mixed solvent of ethyl acetate-toluene (3:1). The solvent was distilled off to give 8-acetoxymethylquinoline (0.86 g).

1. temperatureheated for 2 hours at 80° to 90° C
2. distillationwas distilled off
3. extractionthe residue was extracted with a mixed solvent of ethyl acetate-toluene (3:1)
4. distillationThe solvent was distilled off