Nitric Acid → N-(5-nitro-indan-2-yl)-acetamide
反応式
[C:1]([NH:4][CH:5]1[CH2:13][C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH2:6]1)(=[O:3])[CH3:2].[N+:14]([O-])([OH:16])=[O:15]>>[C:1]([NH:4][CH:5]1[CH2:13][C:12]2[C:7](=[CH:8][CH:9]=[C:10]([N+:14]([O-:16])=[O:15])[CH:11]=2)[CH2:6]1)(=[O:3])[CH3:2]参加物
3
実験手順
20.5 g of 2-acetylaminoindan is added gradually into 200 ml of fuming nitric acid under cooling. After the reaction, the reaction mixture is poured onto 100 g of ice, and the solvent is evaporated from the chloroform extract, and the residue is recrystallized from isopropyl alcohol to give 18.6 g of 2-acetylamino-5-nitroindan.
後処理
- temperatureunder cooling
- customAfter the reaction
- customthe solvent is evaporated from the chloroform
- extractionextract
- customthe residue is recrystallized from isopropyl alcohol
出典と根拠
- ORDレコード
- ord-121b83492bf444a3b2d438e6d8c26b8d
- 出典データセット
- uspto-grants-1990_10
- 特許番号
- US04963587
反応ノート
読み込み中…