Chloroacetyl chloride → 3,7-Bis(2-chloroacetamido)dibenzothiophene 5,5-dioxide

HRID 1089191

反応式

HRID 1089191 の反応式
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[C:9]3[CH:10]=[CH:11][C:12]([NH2:14])=[CH:13][C:8]=3[S:7](=[O:16])(=[O:15])[C:6]=2[CH:17]=1.[Cl:18][CH2:19][C:20](Cl)=[O:21]>CC(C)=O>[Cl:18][CH2:19][C:20]([NH:1][C:2]1[CH:3]=[CH:4][C:5]2[C:9]3[CH:10]=[CH:11][C:12]([NH:14][C:20](=[O:21])[CH2:19][Cl:18])=[CH:13][C:8]=3[S:7](=[O:16])(=[O:15])[C:6]=2[CH:17]=1)=[O:21]

参加物

4

反応物 2

HCID 6577Chloroacetyl chlorideHCID 804123,7-Diaminodibenzothiophene-5,5-dioxide

生成物 1

HCID 221607093,7-Bis(2-chloroacetamido)dibenzothiophene 5,5-dioxide

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

反応条件

温度
100 °C

実験手順

A slurry of 21.8 g of 3,7-diaminodibenzothiophene S,S-dioxide in 400 ml of acetone was cooled in an ice bath while 30.2 ml of chloroacetyl chloride was carefully added. The bath was removed and the mixture heated at 100° C. with stirring, then cooled and poured into ice water. The precipitate was collected, washed with water and dried giving 34.9 g of the desired product as a solid.

後処理

  1. additionwas carefully added
  2. customThe bath was removed
  3. temperaturecooled
  4. additionpoured into ice water
  5. customThe precipitate was collected
  6. washwashed with water
  7. customdried

出典と根拠

ORDレコード
ord-684a764440fd4ba3ac92f8a5407e739b
出典データセット
uspto-grants-1990_10
特許番号
US04965284

関連ノート

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