Hydrochloric Acid → HCID 178432398、化合物

HRID 1089527ノート

反応式

HRID 1089527 の反応式
[SH:1][C:2]1[N:7]2[N:8]=[C:9]([CH3:11])[N:10]=[C:6]2[N:5]=[C:4]([C:12]([O:14]C)=[O:13])[CH:3]=1.[OH-].[Na+].Cl>>[C:12]([C:4]1[CH:3]=[C:2]([SH:1])[N:7]2[N:8]=[C:9]([CH3:11])[N:10]=[C:6]2[N:5]=1)([OH:14])=[O:13]

参加物

4

反応物 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 178498634HCID 178498634、化合物

生成物 1

HCID 178432398HCID 178432398、化合物収率 99.1%

実験手順

A mixture of 7.7 g (34 mmole) of 7-mercapto-5-methoxycarbonyl-2-methyl-s-triazolo[1,5-a]pyrimidine and 70 ml of a 2N NaOH was stirred at room temperature for 2 hours and then ice-cooled. The pH of the mixture was adjusted to 2 with 6N HCl. The precipitates were collected by filtration and washed with water and then acetone, followed by drying, to obtain 7.08 g of the title compound (Yield: 99%).

後処理

  1. temperatureice-cooled
  2. filtrationThe precipitates were collected by filtration
  3. washwashed with water
  4. customby drying

出典と根拠

ORDレコード
ord-7c9374ae16a34cd0b0f16eedbcf77f02
出典データセット
uspto-grants-1990_10
特許番号
US04966900

反応ノート

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