Thionyl Chloride → 3-(1-Methylfluoren-9-yl)propionyl Chloride

HRID 1089854ノート

反応式

HRID 1089854 の反応式
[CH3:1][C:2]1[C:14]2[CH:13]([CH2:15][CH2:16][C:17]([OH:19])=O)[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[C:6]=2[CH:5]=[CH:4][CH:3]=1.O=S(Cl)[Cl:22]>>[CH3:1][C:2]1[C:14]2[CH:13]([CH2:15][CH2:16][C:17]([Cl:22])=[O:19])[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[C:6]=2[CH:5]=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 150450953-(1-Methylfluoren-9-yl)propionic acid

生成物 1

HCID 150450963-(1-Methylfluoren-9-yl)propionyl Chloride

実験手順

3-(1-Methylfluoren-9-yl)propionic acid (2.5 g, 9.9 mmol) was charged with SOCl2 (20 mL, in excess) at room temperature. The reaction mixture was boiled for 2 hr. Excess of thionyl chloride was removed under reduced pressure. The residual oil was used for the next step without further purification.

後処理

  1. customExcess of thionyl chloride was removed under reduced pressure
  2. customThe residual oil was used for the next step without further purification

出典と根拠

ORDレコード
ord-f72077c274bc48209040beb6f717b564
出典データセット
uspto-grants-1992_01
特許番号
US05079260

反応ノート

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