Methyl 2,2-dimethyl-4-oxohexanoate → 3-[1-(4-Chlorobenzyl)-3-methyl-5-methoxyindol-2-yl]-2,2-dimethylpropanoic acid
反応式
Cl.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][N:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)N)=[CH:5][CH:4]=1.[CH3:20][C:21]([CH3:31])([CH2:26][C:27](=O)[CH2:28][CH3:29])[C:22]([O:24]C)=[O:23]>C(O)(C)(C)C>[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][N:10]2[C:12]3[C:17](=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=3)[C:28]([CH3:29])=[C:27]2[CH2:26][C:21]([CH3:31])([CH3:20])[C:22]([OH:24])=[O:23])=[CH:5][CH:4]=1参加物
4
実験手順
Following the method of Example 2, but using 1-[(4-chlorophenyl)methyl]-1-(4-methoxyphenyl)hydrazine hydrochloride and methyl 2,2-dimethyl-4-oxohexanoate as the starting materials and tert-butanol as the solvent, the title compound was prepared.