3,5-Dimethyl-4-nitro-I,2-(methylenedioxy)benzene → 2,6-Dimethyl-3,4-(methylenedioxy)aniline

HRID 1090631ノート

反応式

HRID 1090631 の反応式
[CH3:1][C:2]1[C:3]2[O:14][CH2:13][O:12][C:4]=2[CH:5]=[C:6]([CH3:11])[C:7]=1[N+:8]([O-])=O.[H][H]>[Pd].C(O)C>[CH3:1][C:2]1[C:3]2[O:14][CH2:13][O:12][C:4]=2[CH:5]=[C:6]([CH3:11])[C:7]=1[NH2:8]

参加物

5

反応物 2

HCID 199138223,5-Dimethyl-4-nitro-I,2-(methylenedioxy)benzeneHCID 178418361HCID 178418361、化合物

生成物 1

HCID 199138202,6-Dimethyl-3,4-(methylenedioxy)aniline収率 68%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

3,5-Dimethyl-4-nitro-I,2-(methylenedioxy)benzene (5.0 g) and 10% palladium on charcoal catalyst (1.2 g) in ethanol (250 ml) was shaken in a hydrogen atmosphere (50 p.s.i.) at 40° C. for 4 hours. The mixture was filtered through celite and evaporated to leave 2,6-dimethyl-3,4-(methylenedioxy)aniline (2.8 g, 68%) as a dark oil.

後処理

  1. filtrationThe mixture was filtered through celite
  2. customevaporated

出典と根拠

ORDレコード
ord-7f37fbeb302c400d979062df539b2ab5
出典データセット
uspto-grants-1992_01
特許番号
US05082848

反応ノート

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