Hydrochloric Acid → 3,3-dimethoxypropanoic Acid
反応式
[CH3:1][O:2][CH:3]([O:9][CH3:10])[CH2:4][C:5]([O:7]C)=[O:6].Cl>[OH-].[Na+].O>[CH3:1][O:2][CH:3]([O:9][CH3:10])[CH2:4][C:5]([OH:7])=[O:6]参加物
5
実験手順
50 g (0.33 mol.) of Methyl 3,3-dimethoxy-propanoate in 200 ml of 2N NaOH solution in water were refluxed 2 hours. After cooling the solution was acidified with hydrochloric acid then extracted two times with 200 ml of CH2Cl2. The extracts were dried on sodium sulfate and evaporated to leave 35 g (Yield=78%) of 3,3-dimethoxy-propanoic acid as an oil.
後処理
- temperatureAfter cooling the solution
- extractionthen extracted two times with 200 ml of CH2Cl2
- customThe extracts were dried on sodium sulfate
- customevaporated
出典と根拠
- ORDレコード
- ord-8da6dea0eb444563af2b044a97b7fe22
- 出典データセット
- uspto-grants-1992_01
- 特許番号
- US05082847
反応ノート
読み込み中…