化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Hydroxide → 4-(quinolin-2-ylmethoxy)benzoic Acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Methyl 4-(2-quinolinylmethoxy)benzoate | HCID 19934817 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 4-(quinolin-2-ylmethoxy)benzoic Acid | HCID 9838552 | 65.5% |
反応手順
5.00 g of methyl-4-(quinolin-2-ylmethoxy)benzoate is dissolved in 120 ml of ethanol and 90 ml of 1N sodium hydroxide and the mixture is stirred at room temperature for 4 days. The mixture is concentrated in vacuo to remove the ethanol. The residue is diluted with water, acidified to pH 6 and the resulting solid is filtered off and recrystallized from methanol to give 3.12 g 4-(quinolin-2-ylmethoxy)benzoic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05082849 |
| 出典データセット | uspto-grants-1992_01 |
| ORD ID | ord-813a8b5498a34ca9a99a75095311e39c |
| 出典メモ | uspto-grants-1992_01 |