反应详情

5.00 g of methyl-4-(quinolin-2-ylmethoxy)benzoate is dissolved in 120 ml of ethanol and 90 ml of 1N sodium hydroxide and the mixture is stirred at room temperature for 4 days. The mixture is concentrated in vacuo to remove the ethanol. The residue is diluted with water, acidified to pH 6 and the resulting solid is filtered off and recrystallized from methanol to give 3.12 g 4-(quinolin-2-ylmethoxy)benzoic acid.

1. concentrationThe mixture is concentrated in vacuo
2. customto remove the ethanol
3. additionThe residue is diluted with water
4. filtrationthe resulting solid is filtered off
5. customrecrystallized from methanol