HCID 53672027、化合物 → 12,12,12-trifluorododecanoic Acid
反応式
[F:1][C:2]([F:17])([F:16])[CH2:3][CH2:4][CH:5]=[CH:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14]>C(O)C.[Pd]>[F:1][C:2]([F:16])([F:17])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14]参加物
4
実験手順
Dissolve 12,12,12-trifluoro-8-dodecenoic acid (1.39 g, 5.5 mmol) in ethanol (50 mL) and place in a Paar hydrogenation flask. Add 10% palladium/carbon (500 mg). Charge the vessel to 50 psi and shake for 18 hours. Filter through celite and remove the solvent in vacuo to give 12,12,12-trifluorododecanoic acid.
後処理
- additionCharge the vessel to 50 psi
- filtrationFilter through celite
- customremove the solvent in vacuo
出典と根拠
- ORDレコード
- ord-eff658b46e1948b8a756cfcfb15a00b1
- 出典データセット
- uspto-grants-1992_01
- 特許番号
- US05084461
反応ノート
読み込み中…