反応式
[NH2:1][C:2]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([O:12][CH3:13])=[CH:6][C:3]=1[C:4]#[N:5].[CH2:14](N)[CH2:15][NH2:16]>O.P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=S>[NH:5]1[CH2:14][CH2:15][N:16]=[C:4]1[C:3]1[CH:6]=[C:7]([O:12][CH3:13])[C:8]([O:10][CH3:11])=[CH:9][C:2]=1[NH2:1]参加物
5
実験手順
2-Amino-4,5-dimethoxybenzonitrile (5.0 g, 28 mmol) was added to ethylenediamine (7.9 g, 131 mmol) at room temperature. The resulting solution was warmed to 40., and a catalytic amount of diphosphorus pentasulfide (50 mg) was added. The mixture was heated to 80-90, and the stirring was continued overnight. The reaction mixture was diluted with water, and the resulting precipitate was collected by filtration to give 2-(4,5-dihydro-1H-imidazol-2-yl)-4,5-dimethoxyaniline (5.1 g, 82%) as a solid.
後処理
- temperatureThe resulting solution was warmed to 40
- temperatureThe mixture was heated to 80-90
- filtrationthe resulting precipitate was collected by filtration
出典と根拠
- ORDレコード
- ord-262f0e17b6ed4d36a659c36a8736429d
- 出典データセット
- uspto-grants-2012_03
- 特許番号
- US08129386B2
関連ノート
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