関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Formamide | HCID 713 | — |
| 反応物 | 2-Aminoterephthalic acid | HCID 2724822 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | 4-Oxo-3,4-dihydroquinazoline-7-carboxylic acid | HCID 135483588 | 80% |
反応手順
A mixture of 2-amino terephthalic acid (2 g, 11 mmol) and formamide (10 mL) was heated at 180° C. for 5 h. The reaction mixture was cooled to RT and acetone was added. The solid precipitated thus obtained was stirred for 2 h, filtered and dried to give 4-oxo-3,4-dihydroquinazoline-7-carboxylic acid in 80% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08133998B2 |
|---|
| 出典データセット | uspto-grants-2012_03 |
|---|
| ORD ID | ord-5c776617c0e549368e39fa55bb317b23 |
|---|
| 出典メモ | uspto-grants-2012_03 |
|---|
