Acetic Anhydride → Ethyl (acetyloxy)(4-chloro-3-nitrophenyl)acetate

HRID 1096473ノート

反応式

HRID 1096473 の反応式
[CH2:1]([O:3][C:4](=[O:17])[CH:5]([C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[C:9]([N+:14]([O-:16])=[O:15])[CH:8]=1)[OH:6])[CH3:2].[C:18](OC(=O)C)(=[O:20])[CH3:19]>N1C=CC=CC=1>[CH2:1]([O:3][C:4](=[O:17])[CH:5]([O:6][C:18](=[O:20])[CH3:19])[C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[C:9]([N+:14]([O-:16])=[O:15])[CH:8]=1)[CH3:2]

参加物

4

反応物 2

HCID 7918Acetic AnhydrideHCID 86609828Ethyl (4-chloro-3-nitrophenyl)(hydroxy)acetate

生成物 1

HCID 86609827Ethyl (acetyloxy)(4-chloro-3-nitrophenyl)acetate

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

To a solution (6 mL) of the compound (1.46 g) prepared in Example 22 in pyridine, acetic anhydride (2 mL) was added, and the mixture was stirred for 1 hour at room temperature. The title compound (135 mg) having the following physical data was obtained by concentrating the reaction mixture and azeotroping in toluene.

出典と根拠

ORDレコード
ord-555d4c3cd5e8463eb2a81316404c49a5
出典データセット
uspto-grants-2012_03
特許番号
US08138335B2

反応ノート

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