Dimethylformamide → HCID 57930995、化合物

HRID 1096984ノート

反応式

HRID 1096984 の反応式
[CH2:1](I)[CH3:2].CN(C=O)C.[Br:9][C:10]1[C:19]([O:20][CH3:21])=[CH:18][C:13]([C:14]([O:16][CH3:17])=[O:15])=[CH:12][C:11]=1[OH:22].C(=O)([O-])[O-].[K+].[K+]>O>[Br:9][C:10]1[C:19]([O:20][CH3:21])=[CH:18][C:13]([C:14]([O:16][CH3:17])=[O:15])=[CH:12][C:11]=1[O:22][CH2:1][CH3:2]

参加物

6

反応物 4

HCID 6228DimethylformamideHCID 6340IodoethaneHCID 11430Potassium CarbonateHCID 57930973HCID 57930973、化合物

生成物 1

HCID 57930995HCID 57930995、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

In a 1.0-liter egg plant-type flaks, ethyl iodide (6.91 mL, 86 mmol) was added to a DMF (150 mL) solution of the previously-obtained methyl 4-bromo-3-hydroxy-5-methoxybenzoate and potassium carbonate (11.9 g, 86 mmol), and stirred overnight at room temperature. Water was added to the reaction solution, the formed precipitate was taken out through filtration and dried under reduced pressure to obtain the title compound as a colorless solid.

後処理

  1. filtrationthe formed precipitate was taken out through filtration
  2. customdried under reduced pressure

出典と根拠

ORDレコード
ord-764ac02837e64c8ab08283cb874b6954
出典データセット
uspto-grants-2012_03
特許番号
US08138197B2

反応ノート

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