Thionyl Chloride → HCID 58087452、化合物
反応式
[CH2:1]([S:4]([NH:7][C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11](O)=[O:12])(=[O:6])=[O:5])[CH2:2][CH3:3].S(Cl)([Cl:19])=O>>[CH2:1]([S:4]([NH:7][C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11]([Cl:19])=[O:12])(=[O:6])=[O:5])[CH2:2][CH3:3]参加物
3
実験手順
A solution of 3-(propane-1-sulfonylamino)-benzoic acid (76, 1.20 g, 4.93 mmol) in thionyl chloride was heated to reflux for 3.0 hours. Evaporation of the solvent gave compound 77 as white solid that was used for the next step.
後処理
- temperatureto reflux for 3.0 hours
- customEvaporation of the solvent
出典と根拠
- ORDレコード
- ord-71a51daeba604277a775a39195617aa3
- 出典データセット
- uspto-grants-2012_03
- 特許番号
- US08143271B2
反応ノート
読み込み中…