Trifluoroacetic acid → N-methyl-N-pyridin-2-ylethane-1,2-diamine trifluoroacetate

HRID 1099095ノート

反応式

HRID 1099095 の反応式
[CH3:1][N:2]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=1)[CH2:3][CH2:4][NH:5]C(=O)OC(C)(C)C.[C:19]([OH:25])([C:21]([F:24])([F:23])[F:22])=[O:20]>C(Cl)Cl>[F:22][C:21]([F:24])([F:23])[C:19]([OH:25])=[O:20].[CH3:1][N:2]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=1)[CH2:3][CH2:4][NH2:5]

参加物

4

反応物 2

HCID 6422Trifluoroacetic acidHCID 59216311Tert-butyl 2-[methyl(pyridin-2-yl)amino]ethylcarbamate

生成物 1

HCID 66813129N-methyl-N-pyridin-2-ylethane-1,2-diamine trifluoroacetate

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

tert-Butyl 2-[methyl(pyridin-2-yl)amino]ethylcarbamate was stirred with DCM (0.5 ml) and TFA (0.5 ml) for 30 min. The volatiles were removed under reduced pressure to yield the product.

後処理

  1. customThe volatiles were removed under reduced pressure
  2. customto yield the product

出典と根拠

ORDレコード
ord-52de3c6fcd584812be89fb6f1cf1a148
出典データセット
uspto-grants-2012_03
特許番号
US08143251B2

反応ノート

読み込み中…