Thionyl Chloride → 2,2-Dichloro-1-(4-ethoxyphenyl)cyclopropane-1-carbonyl chloride

HRID 1105504ノート

反応式

HRID 1105504 の反応式
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2([C:15]([OH:17])=O)[CH2:12][C:11]2([Cl:14])[Cl:13])=[CH:6][CH:5]=1)[CH3:2].S(Cl)([Cl:20])=O>>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2([C:15]([Cl:20])=[O:17])[CH2:12][C:11]2([Cl:14])[Cl:13])=[CH:6][CH:5]=1)[CH3:2]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 135804022,2-Dichloro-1-(4-ethoxyphenyl)cyclopropane-1-carboxylic acid

生成物 1

HCID 130410812,2-Dichloro-1-(4-ethoxyphenyl)cyclopropane-1-carbonyl chloride

実験手順

The 1-p-ethoxyphenyl-2,2-dichlorocyclopropane-1-carboxylic acid (1.38 g) was refluxed on a water bath with thionyl chloride (1.19 g) for 15 minutes. The excess thionyl chloride was then evaporated under vacuum (1 Torr.) and the residue of carbonyl chloride reacted without further purification with one of the alcohols (a), (b), (c) or (d). ##STR11##

後処理

  1. customThe excess thionyl chloride was then evaporated under vacuum (1 Torr.)
  2. customthe residue of carbonyl chloride reacted without further purification with one of the alcohols (a), (b), (c) or (d)

出典と根拠

ORDレコード
ord-f017deee452b45fd8500b156a3507096
出典データセット
uspto-grants-1982_01
特許番号
US04309350

反応ノート

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