N,N-diethyl-2-nitrobenzenesulfonamide → 2-Amino-N,N-diethylbenzenesulfonamide

HRID 1105748ノート

反応式

HRID 1105748 の反応式
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10]([N:13]([CH2:16][CH3:17])[CH2:14][CH3:15])(=[O:12])=[O:11])([O-])=O.[H][H]>[Pd].C(OCC)(=O)C>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[S:10]([N:13]([CH2:16][CH3:17])[CH2:14][CH3:15])(=[O:12])=[O:11]

参加物

5

反応物 2

HCID 4229519N,N-diethyl-2-nitrobenzenesulfonamideHCID 178418361HCID 178418361、化合物2 回

生成物 1

HCID 128195982-Amino-N,N-diethylbenzenesulfonamide収率 104.6%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

In a pressure vessel a mixture of 133 g of o-nitro-N,N-diethylbenzenesulfonamide, 5 g of 10% palladium on carbon, and 500 ml of ethyl acetate was shaken at 130° under 500 psi hydrogen pressure until hydrogen was no longer absorbed. The reaction mixture was cooled and the catalyst filtered off. Evaporation of the solvent in-vacuo gave 123 g of o-amino-N,N-diethylbenzenesulfonamide as a viscous oil which slowly crystallized to a solid, m.p. 45°-51°.

後処理

  1. customwas no longer absorbed
  2. temperatureThe reaction mixture was cooled
  3. filtrationthe catalyst filtered off
  4. customEvaporation of the solvent in-vacuo

出典と根拠

ORDレコード
ord-26f3400be9384ad1bdc3a4d129cbc533
出典データセット
uspto-grants-1982_01
特許番号
US04310346

反応ノート

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