3-(Nitro-n-butylamino)benzophenone → HCID 54315355、化合物

HRID 1105839ノート

反応式

HRID 1105839 の反応式
[N+]([N:4](CCCC)[C:5]1[CH:6]=[C:7]([CH:16]=[CH:17][CH:18]=1)[C:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:9])([O-])=O.[H][H]>C(O)C.[Pd]>[NH2:4][C:5]1[CH:6]=[C:7]([CH:16]=[CH:17][C:18]=1[NH:4][CH2:5][CH2:18][CH2:17][CH3:16])[C:8]([C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)=[O:9]

参加物

5

反応物 2

HCID 205552293-(Nitro-n-butylamino)benzophenoneHCID 178418361HCID 178418361、化合物

生成物 1

HCID 54315355HCID 54315355、化合物収率 88.6%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

To a solution of 3-(nitro-4-n-butylamino)-benzophenone (5.96 g.; 0.02 mole) in ethanol (200 ml.) is added palladium on charcoal (5%; 0.1 g.). The mixture is hydrogenated until theoretical uptake of hydrogen has occurred (about three hours) and then let stand at room temperature overnight. The reaction mixture is filtered to remove the catalyst and the filtrate concentrated under vacuum to afford 4.75 g. (88.6% yield) of 3-amino-4-n-butylaminobenzophenone.

後処理

  1. custom(about three hours)
  2. filtrationThe reaction mixture is filtered
  3. customto remove the catalyst
  4. concentrationthe filtrate concentrated under vacuum
  5. customto afford 4.75 g

出典と根拠

ORDレコード
ord-36486451a3814c69a32801938eb84ea6
出典データセット
uspto-grants-1982_01
特許番号
US04310537

反応ノート

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