Acetone → HCID 12760709、化合物

HRID 1105985ノート

反応式

HRID 1105985 の反応式
[OH:1][CH:2]([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][C:12]([OH:14])=[O:13])[C:3]([OH:5])=[O:4].[CH3:15][C:16]([CH3:18])=O.S(=O)(=O)(O)O.C(=O)([O-])[O-].[Na+].[Na+]>O>[C:12]([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH:2]1[C:3](=[O:5])[O:4][C:16]([CH3:18])([CH3:15])[O:1]1)([OH:14])=[O:13]

参加物

6

反応物 4

HCID 180AcetoneHCID 1118Sulfuric AcidHCID 10340Sodium CarbonateHCID 127607082-Hydroxynonanedioic acid

生成物 1

HCID 12760709HCID 12760709、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A stirred mixture of 10.2 g. of 2-hydroxynonanedioic acid, 50 ml. of acetone, 75 ml. of petroleum ether (b.p. 30°-55° C.), and 0.25 ml. of sulfuric acid is heated at reflux for 7 hours with azeotropic removal of water. The stirred mixture is treated with 0.59 g. of sodium carbonate and diluted with petroleum ether. The solution is decanted from solid and concentrated to give 9.4 g. of oil; pmr (CDCl3) δ 1.58 and 1.63 (gem-dimethyl group).

後処理

  1. additionA stirred mixture of 10.2 g
  2. additionThe stirred mixture is treated with 0.59 g
  3. customThe solution is decanted from solid
  4. concentrationconcentrated
  5. customto give 9.4 g

出典と根拠

ORDレコード
ord-70568d2e85ec4fe7a90a30dc15594975
出典データセット
uspto-grants-1982_01
特許番号
US04310700

反応ノート

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