Lithium Bromide → 4-(Bromomethyl)-1-methyl-2-nitrobenzene
反応式
Cl[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH3:9])=[C:5]([N+:10]([O-:12])=[O:11])[CH:4]=1.[Br-:13].[Li+]>CC(C)=O>[Br:13][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([CH3:9])=[C:5]([N+:10]([O-:12])=[O:11])[CH:4]=1参加物
4
実験手順
4-Chloromethyl-1-methyl-2-nitro-benzene (5 g) was dissolved in 50 ml of acetone and 23.4 g of lithium bromide was added. The reaction mixture was heated at reflux for 18 hr. The solvent was evaporated off and the residue was tritrated with hexane to give 5.3 g of 4-bromomethyl-1-methyl-2-nitro-benzene as a tan solid. ##STR125##
後処理
- temperatureThe reaction mixture was heated
- temperatureat reflux for 18 hr
- customThe solvent was evaporated off
出典と根拠
- ORDレコード
- ord-63388c00adb548319dfba0ce67b6d1dc
- 出典データセット
- uspto-grants-2000_05
- 特許番号
- US06057349
反応ノート
読み込み中…